Trichosanthes Fruit seeds Fructus Trichosanthis seed
Common name:Trichosanthes tricuspidata seeds
Source of anti-HIV agent, Compound Q (GLQ223), extracted from the root. Recent in vitro laboratory studies with Compound Q showed great promise for AIDS treatment because it selectively kills only infected cells, leaving healthy cells untouched; clinical trials are not yet conclusive, however. Used into treat angina pectoris, to reduce phlegm, and since 300 A.D. to induce abortions.
Clearing away heat, resolving sputum, promoting the flow of qi to soothechest oppression,subduing swelling to treat carbuncles, and moistening the bowels to relieve constipa-tion.
1. Cough due tolung-heat withsymptoms of yellow and thick sputum, unsmoothexpectoration,fullness in the chest, dry stools, etc. It is often used with scutellaria root andarisaema treated with bile, as in Bolus for Clearing Heat and Phlegm (Qingqi HuatanWan).
2. Chest pain due to obstruction of qi in the chest. It is often used with macrostem onion, pinellia tuber andwhite wine, namedDecoction of Tricho-santhes, Allium and Pinellia (Gualou Xiebai Banxia Tang). For accumulation ofphlegm-heat in thechest manifested asfeeling of fullnessand stuffiness in the chest and hypochon-drium with tenderness, it is often used with pinellia tuber andcoptis rhizome, named Minor Decoction forRelieving Stuffiness in the Chest (XiaoXianxiong Tang).
3. Carbuncles ofbreast and pulmonary abscess. For red selling with burning pain at the beginning of acute mastitis, itis often used withdandelion and honey-suckle; for pulmonary abscess withpurulent and bloodyexpectoration, it is often used with houttuynia. 4. For drynesssyndrome of theintestines withconstipation, it isoften used with hemp and bush-cherry seed.
Dosage andadministration:10-20g of the entire fruit; 6-12g of the fruit peel; 10-15g of the seed; decocted in water for an oral dose. For obstruction of qi in the chest andsubcutaneous swelling or abscess, it is better to use the entire fruit; for cleaning heat, resolving sputum and promoting the flow of qi to soothe the chestoppression, it ispreferable to usethe fruit peel; forloosening the bowels and relieving consti-pation, the seed should be the choice.